Zdzislaw M Szulc Selected Research

Sphingosine

9/2020	Mechanistic insights into ceramidase inhibitor LCL521-enhanced tumor cell killing by photodynamic and thermal ablation therapies.
1/2017	Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase.
1/2013	LCL124, a cationic analog of ceramide, selectively induces pancreatic cancer cell death by accumulating in mitochondria.
2/2011	Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.

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Zdzislaw M Szulc Research Topics

Disease

18	Neoplasms (Cancer) 01/2022 - 02/2008
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2023 - 10/2016
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2020 - 01/2016
2	Lung Neoplasms (Lung Cancer) 11/2019 - 01/2013
2	Prostatic Neoplasms (Prostate Cancer) 12/2017 - 02/2008
2	Squamous Cell Carcinoma of Head and Neck 01/2017 - 01/2005
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2023
1	Arthritis (Polyarthritis) 11/2020
1	Experimental Arthritis 11/2020
1	Multiple Sclerosis 11/2020
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2017
1	Colitis 01/2017
1	Infections 01/2017
1	Splenomegaly 01/2017
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2016
1	Glioma (Gliomas) 10/2013
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2013
1	Necrosis 01/2013
1	Neurilemmoma (Schwannoma) 07/2012
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2012
1	Neuroblastoma 06/2007

Drug/Important Bio-Agent (IBA)

17	CeramidesIBA 10/2023 - 01/2005
9	Acid CeramidaseIBA 12/2023 - 02/2008
8	SphingolipidsIBA 11/2020 - 09/2010
5	Proteins (Proteins, Gene)FDA Link 01/2019 - 11/2010
4	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2022 - 09/2013
4	SphingosineIBA 09/2020 - 02/2011
4	dihydroceramide desaturaseIBA 09/2013 - 06/2007
3	LCL521IBA 01/2022 - 01/2016
3	sphingosine kinaseIBA 09/2020 - 09/2013
3	Fingolimod Hydrochloride (FTY720)FDA Link 11/2019 - 01/2013
3	BromidesIBA 01/2013 - 02/2011
2	IronIBA 12/2023 - 10/2023
2	Nonmuscle Myosin Type IIAIBA 11/2019 - 01/2019
2	Phosphotransferases (Kinase)IBA 11/2019 - 12/2017
2	N-palmitoylsphingosineIBA 10/2018 - 09/2013
2	EnzymesIBA 09/2013 - 06/2007
1	Histocompatibility Antigens Class IIIBA 11/2020
1	CytokinesIBA 11/2020
1	temoporfinIBA 09/2020
1	PF-543IBA 09/2020
1	CeramidasesIBA 09/2020
1	Phosphates (Orthophosphate)IBA 09/2020
1	IsotopesIBA 01/2019
1	Androgen Receptors (Androgen Receptor)IBA 12/2017
1	glycylpeptide N-tetradecanoyltransferaseIBA 12/2017
1	2-N-(1'-carboxamidino)sphingosineIBA 01/2017
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2017
1	Nonesterified Fatty Acids (NEFA)IBA 01/2017
1	IsoenzymesIBA 01/2017
1	Dextrans (Dextran)FDA Link 01/2017
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2017
1	Peptides (Polypeptides)IBA 01/2017
1	Cisplatin (Platino)FDA LinkGeneric 01/2017
1	Retinoblastoma ProteinIBA 01/2017
1	fms-Like Tyrosine Kinase 3IBA 10/2016
1	VaccinesIBA 01/2016
1	Caspase 3 (Caspase-3)IBA 10/2013
1	Coloring Agents (Dyes)IBA 10/2013
1	2'-hydroxy C16-ceramideIBA 10/2013
1	Annexin A5IBA 10/2013
1	ChromatinIBA 10/2013
1	Photosensitizing Agents (Photosensitizers)IBA 09/2013
1	PorphyrinsIBA 09/2013
1	D- erythro- 2- N- (160- (1''- pyridinium)hexadecanoyl)sphingosine bromideIBA 09/2013
1	silicon phthalocyanineIBA 09/2013
1	Dihematoporphyrin Ether (Porfimer Sodium)FDA Link 09/2013
1	Gemcitabine FDA Link 01/2013
1	2- N- (6'- (1'- pyridinium)hexanoyl)sphingosineIBA 01/2013
1	Sodium SeleniteIBA 10/2012
1	Biotin (Vitamin H)FDA Link 07/2012
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2012
1	LipidsIBA 11/2010
1	Alkaline CeramidaseIBA 09/2010
1	FenretinideIBA 09/2010
1	RetinoidsIBA 09/2010
1	safingol (sphinganine)IBA 09/2010
1	CaspasesIBA 03/2009
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2005

Therapy/Procedure

6	Therapeutics 01/2022 - 11/2010
4	Photochemotherapy (Photodynamic Therapy) 01/2022 - 09/2013
3	Drug Therapy (Chemotherapy) 01/2017 - 01/2005
1	Cryosurgery 09/2020
1	Photothermal Therapy 09/2020
1	Radiotherapy 01/2017